CHM 320 – Laboratory Projects Spring , 2013
نویسنده
چکیده
The Suzuki cross-coupling reaction is about 30 years old and represents a smooth method for creating carbon-carbon bonds. Typically, in the Suzuki reaction aryl halides are combined with an aryl boronic acid or boronic ester in the presence of a Pd(0) catalyst and base to afford a variety of biaryl compounds (Scheme 1). These biphenyl templates are very common in non-steroidal anti-inflammatory drugs (NSAIDs).
منابع مشابه
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